diff --git a/src-tauri/src/types.rs b/src-tauri/src/types.rs
index cf93e7b3f..05deb065f 100644
--- a/src-tauri/src/types.rs
+++ b/src-tauri/src/types.rs
@@ -312,6 +312,8 @@ pub(crate) struct AppSettings {
         rename = "composerReasoningShortcut"
     )]
     pub(crate) composer_reasoning_shortcut: Option<String>,
+    #[serde(default = "default_interrupt_shortcut", rename = "interruptShortcut")]
+    pub(crate) interrupt_shortcut: Option<String>,
     #[serde(
         default = "default_composer_collaboration_shortcut",
         rename = "composerCollaborationShortcut"
@@ -505,6 +507,15 @@ fn default_composer_reasoning_shortcut() -> Option<String> {
     Some("cmd+shift+r".to_string())
 }
 
+fn default_interrupt_shortcut() -> Option<String> {
+    let value = if cfg!(target_os = "macos") {
+        "ctrl+c"
+    } else {
+        "ctrl+shift+c"
+    };
+    Some(value.to_string())
+}
+
 fn default_composer_collaboration_shortcut() -> Option<String> {
     Some("shift+tab".to_string())
 }
@@ -694,6 +705,7 @@ impl Default for AppSettings {
             composer_model_shortcut: default_composer_model_shortcut(),
             composer_access_shortcut: default_composer_access_shortcut(),
             composer_reasoning_shortcut: default_composer_reasoning_shortcut(),
+            interrupt_shortcut: default_interrupt_shortcut(),
             composer_collaboration_shortcut: default_composer_collaboration_shortcut(),
             new_agent_shortcut: default_new_agent_shortcut(),
             new_worktree_agent_shortcut: default_new_worktree_agent_shortcut(),
@@ -768,6 +780,12 @@ mod tests {
             settings.composer_collaboration_shortcut.as_deref(),
             Some("shift+tab")
         );
+        let expected_interrupt = if cfg!(target_os = "macos") {
+            "ctrl+c"
+        } else {
+            "ctrl+shift+c"
+        };
+        assert_eq!(settings.interrupt_shortcut.as_deref(), Some(expected_interrupt));
         assert_eq!(
             settings.toggle_debug_panel_shortcut.as_deref(),
             Some("cmd+shift+d")
diff --git a/src/App.tsx b/src/App.tsx
index 15954c9c6..a1fd03660 100644
--- a/src/App.tsx
+++ b/src/App.tsx
@@ -82,6 +82,7 @@ import { useAppMenuEvents } from "./features/app/hooks/useAppMenuEvents";
 import { useWorkspaceActions } from "./features/app/hooks/useWorkspaceActions";
 import { useWorkspaceCycling } from "./features/app/hooks/useWorkspaceCycling";
 import { useThreadRows } from "./features/app/hooks/useThreadRows";
+import { useInterruptShortcut } from "./features/app/hooks/useInterruptShortcut";
 import { useLiquidGlassEffect } from "./features/app/hooks/useLiquidGlassEffect";
 import { useCopyThread } from "./features/threads/hooks/useCopyThread";
 import { useTerminalController } from "./features/terminal/hooks/useTerminalController";
@@ -1208,6 +1209,14 @@ function MainApp() {
     onDropPaths: handleDropWorkspacePaths,
   });
 
+  useInterruptShortcut({
+    isEnabled: canInterrupt,
+    shortcut: appSettings.interruptShortcut,
+    onTrigger: () => {
+      void interruptTurn();
+    },
+  });
+
   const {
     handleSelectPullRequest,
     resetPullRequestSelection,
diff --git a/src/features/app/hooks/useInterruptShortcut.ts b/src/features/app/hooks/useInterruptShortcut.ts
new file mode 100644
index 000000000..b1073a69b
--- /dev/null
+++ b/src/features/app/hooks/useInterruptShortcut.ts
@@ -0,0 +1,40 @@
+import { useEffect } from "react";
+import { matchesShortcut } from "../../../utils/shortcuts";
+
+type UseInterruptShortcutOptions = {
+  isEnabled: boolean;
+  shortcut: string | null;
+  onTrigger: () => void | Promise<void>;
+};
+
+export function useInterruptShortcut({
+  isEnabled,
+  shortcut,
+  onTrigger,
+}: UseInterruptShortcutOptions) {
+  useEffect(() => {
+    if (!isEnabled || !shortcut) {
+      return;
+    }
+    const handleKeyDown = (event: KeyboardEvent) => {
+      if (event.repeat || event.defaultPrevented) {
+        return;
+      }
+      const target = event.target;
+      if (
+        target instanceof HTMLElement &&
+        (target.isContentEditable ||
+          target.closest("input, textarea, select, [contenteditable='true']"))
+      ) {
+        return;
+      }
+      if (!matchesShortcut(event, shortcut)) {
+        return;
+      }
+      event.preventDefault();
+      void onTrigger();
+    };
+    window.addEventListener("keydown", handleKeyDown);
+    return () => window.removeEventListener("keydown", handleKeyDown);
+  }, [isEnabled, onTrigger, shortcut]);
+}
diff --git a/src/features/settings/components/SettingsView.test.tsx b/src/features/settings/components/SettingsView.test.tsx
index 129a17b15..0be55fa9f 100644
--- a/src/features/settings/components/SettingsView.test.tsx
+++ b/src/features/settings/components/SettingsView.test.tsx
@@ -28,6 +28,7 @@ const baseSettings: AppSettings = {
   composerAccessShortcut: null,
   composerReasoningShortcut: null,
   composerCollaborationShortcut: null,
+  interruptShortcut: null,
   newAgentShortcut: null,
   newWorktreeAgentShortcut: null,
   newCloneAgentShortcut: null,
diff --git a/src/features/settings/components/SettingsView.tsx b/src/features/settings/components/SettingsView.tsx
index b720f4990..b2cfe9cce 100644
--- a/src/features/settings/components/SettingsView.tsx
+++ b/src/features/settings/components/SettingsView.tsx
@@ -24,7 +24,11 @@ import type {
   WorkspaceInfo,
 } from "../../../types";
 import { formatDownloadSize } from "../../../utils/formatting";
-import { buildShortcutValue, formatShortcut } from "../../../utils/shortcuts";
+import {
+  buildShortcutValue,
+  formatShortcut,
+  getDefaultInterruptShortcut,
+} from "../../../utils/shortcuts";
 import { clampUiScale } from "../../../utils/uiScale";
 import { getCodexConfigPath } from "../../../services/tauri";
 import {
@@ -174,6 +178,7 @@ type ShortcutSettingKey =
   | "composerAccessShortcut"
   | "composerReasoningShortcut"
   | "composerCollaborationShortcut"
+  | "interruptShortcut"
   | "newAgentShortcut"
   | "newWorktreeAgentShortcut"
   | "newCloneAgentShortcut"
@@ -190,6 +195,7 @@ type ShortcutDraftKey =
   | "access"
   | "reasoning"
   | "collaboration"
+  | "interrupt"
   | "newAgent"
   | "newWorktreeAgent"
   | "newCloneAgent"
@@ -209,6 +215,7 @@ const shortcutDraftKeyBySetting: Record<ShortcutSettingKey, ShortcutDraftKey> =
   composerAccessShortcut: "access",
   composerReasoningShortcut: "reasoning",
   composerCollaborationShortcut: "collaboration",
+  interruptShortcut: "interrupt",
   newAgentShortcut: "newAgent",
   newWorktreeAgentShortcut: "newWorktreeAgent",
   newCloneAgentShortcut: "newCloneAgent",
@@ -304,6 +311,7 @@ export function SettingsView({
     access: appSettings.composerAccessShortcut ?? "",
     reasoning: appSettings.composerReasoningShortcut ?? "",
     collaboration: appSettings.composerCollaborationShortcut ?? "",
+    interrupt: appSettings.interruptShortcut ?? "",
     newAgent: appSettings.newAgentShortcut ?? "",
     newWorktreeAgent: appSettings.newWorktreeAgentShortcut ?? "",
     newCloneAgent: appSettings.newCloneAgentShortcut ?? "",
@@ -405,6 +413,7 @@ export function SettingsView({
       access: appSettings.composerAccessShortcut ?? "",
       reasoning: appSettings.composerReasoningShortcut ?? "",
       collaboration: appSettings.composerCollaborationShortcut ?? "",
+      interrupt: appSettings.interruptShortcut ?? "",
       newAgent: appSettings.newAgentShortcut ?? "",
       newWorktreeAgent: appSettings.newWorktreeAgentShortcut ?? "",
       newCloneAgent: appSettings.newCloneAgentShortcut ?? "",
@@ -422,6 +431,7 @@ export function SettingsView({
     appSettings.composerModelShortcut,
     appSettings.composerReasoningShortcut,
     appSettings.composerCollaborationShortcut,
+    appSettings.interruptShortcut,
     appSettings.newAgentShortcut,
     appSettings.newWorktreeAgentShortcut,
     appSettings.newCloneAgentShortcut,
@@ -2022,6 +2032,30 @@ export function SettingsView({
                     Default: {formatShortcut("shift+tab")}
                   </div>
                 </div>
+                <div className="settings-field">
+                  <div className="settings-field-label">Stop active run</div>
+                  <div className="settings-field-row">
+                    <input
+                      className="settings-input settings-input--shortcut"
+                      value={formatShortcut(shortcutDrafts.interrupt)}
+                      onKeyDown={(event) =>
+                        handleShortcutKeyDown(event, "interruptShortcut")
+                      }
+                      placeholder="Type shortcut"
+                      readOnly
+                    />
+                    <button
+                      type="button"
+                      className="ghost settings-button-compact"
+                      onClick={() => void updateShortcut("interruptShortcut", null)}
+                    >
+                      Clear
+                    </button>
+                  </div>
+                  <div className="settings-help">
+                    Default: {formatShortcut(getDefaultInterruptShortcut())}
+                  </div>
+                </div>
                 <div className="settings-divider" />
                 <div className="settings-subsection-title">Panels</div>
                 <div className="settings-subsection-subtitle">
diff --git a/src/features/settings/hooks/useAppSettings.test.ts b/src/features/settings/hooks/useAppSettings.test.ts
index c84284b5e..04e8a684d 100644
--- a/src/features/settings/hooks/useAppSettings.test.ts
+++ b/src/features/settings/hooks/useAppSettings.test.ts
@@ -68,6 +68,7 @@ describe("useAppSettings", () => {
     expect(result.current.settings.codeFontFamily).toContain("SF Mono");
     expect(result.current.settings.backendMode).toBe("local");
     expect(result.current.settings.dictationModelId).toBe("base");
+    expect(result.current.settings.interruptShortcut).toBeTruthy();
   });
 
   it("persists settings via updateAppSettings and updates local state", async () => {
diff --git a/src/features/settings/hooks/useAppSettings.ts b/src/features/settings/hooks/useAppSettings.ts
index 4d6296426..d41e9e550 100644
--- a/src/features/settings/hooks/useAppSettings.ts
+++ b/src/features/settings/hooks/useAppSettings.ts
@@ -15,6 +15,7 @@ import {
   OPEN_APP_STORAGE_KEY,
 } from "../../app/constants";
 import { normalizeOpenAppTargets } from "../../app/utils/openApp";
+import { getDefaultInterruptShortcut } from "../../../utils/shortcuts";
 
 const allowedThemes = new Set(["system", "light", "dark"]);
 
@@ -29,6 +30,7 @@ const defaultSettings: AppSettings = {
   composerAccessShortcut: "cmd+shift+a",
   composerReasoningShortcut: "cmd+shift+r",
   composerCollaborationShortcut: "shift+tab",
+  interruptShortcut: getDefaultInterruptShortcut(),
   newAgentShortcut: "cmd+n",
   newWorktreeAgentShortcut: "cmd+shift+n",
   newCloneAgentShortcut: "cmd+alt+n",
diff --git a/src/types.ts b/src/types.ts
index 062de07e3..ddd90638c 100644
--- a/src/types.ts
+++ b/src/types.ts
@@ -117,6 +117,7 @@ export type AppSettings = {
   composerAccessShortcut: string | null;
   composerReasoningShortcut: string | null;
   composerCollaborationShortcut: string | null;
+  interruptShortcut: string | null;
   newAgentShortcut: string | null;
   newWorktreeAgentShortcut: string | null;
   newCloneAgentShortcut: string | null;
diff --git a/src/utils/shortcuts.ts b/src/utils/shortcuts.ts
index cbf420a54..0d6eb1cf6 100644
--- a/src/utils/shortcuts.ts
+++ b/src/utils/shortcuts.ts
@@ -149,6 +149,17 @@ export function matchesShortcut(event: KeyboardEvent, value: string | null | und
   );
 }
 
+export function isMacPlatform(): boolean {
+  if (typeof navigator === "undefined") {
+    return false;
+  }
+  return /Mac|iPhone|iPad|iPod/.test(navigator.platform);
+}
+
+export function getDefaultInterruptShortcut(): string {
+  return isMacPlatform() ? "ctrl+c" : "ctrl+shift+c";
+}
+
 export function toMenuAccelerator(value: string | null | undefined): string | null {
   const parsed = parseShortcut(value);
   if (!parsed) {