diff --git a/.github/workflows/build-mac.yml b/.github/workflows/build-mac.yml
new file mode 100644
index 000000000..368c6775a
--- /dev/null
+++ b/.github/workflows/build-mac.yml
@@ -0,0 +1,76 @@
+name: "Build and Test pyEXP on Mac"
+
+on:
+  push:
+    branches:
+      - '*'
+  pull_request:
+    branches:
+      - main
+      - devel
+jobs:
+  exp:
+    strategy:
+      matrix:
+        os: [macos-latest]
+
+    name: "Test pyEXP Build on Mac"
+    runs-on: ${{ matrix.os }}
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v4
+        with:
+          submodules: recursive
+
+      - name: Install EXP dependencies (Mac)
+        run: |
+          brew install eigen fftw open-mpi hdf5 libomp
+
+          echo CC=mpicc >> $GITHUB_ENV
+          echo CXX=mpicxx >> $GITHUB_ENV
+          echo OMPI_CC="clang" >> $GITHUB_ENV
+          echo OMPI_CXX="clang++" >> $GITHUB_ENV
+
+          echo OMP_HOME=${HOMEBREW_PATH}/opt/libomp/ >> $GITHUB_ENV
+          echo LDFLAGS="-L${OMP_HOME}/lib" >> $GITHUB_ENV
+          echo CPPFLAGS="-I${OMP_HOME}/include" >> $GITHUB_ENV
+
+      - name: Build EXP
+        run: |
+          # Get Python version info
+          PYTHON_VERSION=$(python -c "import sys; print(f'{sys.version_info.major}.{sys.version_info.minor}')")
+          PYTHON_EXEC=$(which python)
+          PYTHON_LIBRARY_PATH=$(python -c "import sysconfig; print(sysconfig.get_config_var('LIBDIR'))")
+
+          # Set Python library path based on OS
+          if [[ "$RUNNER_OS" == "macOS" ]]; then
+            PYTHON_LIBRARY=${PYTHON_LIBRARY_PATH}/libpython${PYTHON_VERSION}.dylib
+          else
+            PYTHON_LIBRARY=${PYTHON_LIBRARY_PATH}/libpython${PYTHON_VERSION}.so
+          fi
+
+          cmake -G Ninja -B build \
+            -DCMAKE_INSTALL_RPATH=$PWD/install/lib \
+            --install-prefix $PWD/install \
+            -DENABLE_NBODY=YES \
+            -DENABLE_PYEXP=YES \
+            -DDISABLE_OPENMP_COMPILE_FLAGS=YES \
+            -DPYTHON_EXECUTABLE=${PYTHON_EXEC} \
+            -DPYTHON_LIBRARY=${PYTHON_LIBRARY} \
+            -DOpenMP_CXX_INCLUDE_DIR=${OMP_HOME}/include \
+            -DOpenMP_C_INCLUDE_DIR=${OMP_HOME}/include
+
+          # Build and install EXP
+          cmake --build build
+          cmake --install build
+
+          # Add the pyEXP dir as a pyEXP.pth file in Python site-packages:
+          SITE_PACKAGES=$(python -c "import site; print(site.getsitepackages()[0])")
+          echo "$PWD/install/lib/python${PYTHON_VERSION}/site-packages" > "${SITE_PACKAGES}/pyEXP.pth"
+
+      - name: CTest Quick
+        run: ctest --output-on-failure -L quick
+
+      - name: Test pyEXP
+        run: |
+          python -c "import pyEXP; print('pyEXP successfully imported')"
diff --git a/expui/CMakeLists.txt b/expui/CMakeLists.txt
index 25f438d0a..4472dbaa7 100644
--- a/expui/CMakeLists.txt
+++ b/expui/CMakeLists.txt
@@ -58,6 +58,8 @@ add_executable(testread   testread.cc)
 foreach(program ${bin_PROGRAMS})
   target_link_libraries(${program} expui exputil ${common_LINKLIB})
   target_include_directories(${program} PUBLIC ${common_INCLUDE})
-  target_compile_options(${program} PUBLIC ${OpenMP_CXX_FLAGS})
+  if(NOT DISABLE_OPENMP_COMPILE_FLAGS)
+    target_compile_options(${program} PUBLIC ${OpenMP_CXX_FLAGS})
+  endif()
   install(TARGETS ${program} DESTINATION bin)
 endforeach()
diff --git a/pyEXP/CMakeLists.txt b/pyEXP/CMakeLists.txt
index dc8cebf0e..be04e98ae 100644
--- a/pyEXP/CMakeLists.txt
+++ b/pyEXP/CMakeLists.txt
@@ -40,7 +40,9 @@ pybind11_add_module(pyEXP PyWrappers.cc CoefWrappers.cc
   ParticleReaderWrappers.cc MSSAWrappers.cc EDMDWrappers.cc)
 target_link_libraries(pyEXP PUBLIC expui exputil ${common_LINKLIB})
 target_include_directories(pyEXP PUBLIC ${common_INCLUDE})
-target_compile_options(pyEXP PUBLIC ${OpenMP_CXX_FLAGS})
+if(NOT DISABLE_OPENMP_COMPILE_FLAGS)
+  target_compile_options(${program} PUBLIC ${OpenMP_CXX_FLAGS})
+endif()
 get_target_property(cxxflags pyEXP COMPILE_OPTIONS)
 message("The project has set the following flags: ${cxxflags}")