diff --git a/.github/workflows/build_binaries_cmake.yml b/.github/workflows/build_binaries_cmake.yml
index 149d6a083..b124c78ab 100644
--- a/.github/workflows/build_binaries_cmake.yml
+++ b/.github/workflows/build_binaries_cmake.yml
@@ -27,7 +27,7 @@ jobs:
           - os: windows-latest
             c_compiler: cl
             cpp_compiler: cl
-            build_physiboss: "OFF"
+            build_physiboss: "ON"
           - os: ubuntu-latest
             c_compiler: gcc
             cpp_compiler: g++
diff --git a/.github/workflows/tests_cmake.yml b/.github/workflows/tests_cmake.yml
index 25f9a3117..a7b80ce78 100644
--- a/.github/workflows/tests_cmake.yml
+++ b/.github/workflows/tests_cmake.yml
@@ -36,7 +36,7 @@ jobs:
           {"use_physiboss": false, cwd: "build/sample_projects/episode", name: "PhysiCell Episode", binary: "episode", max_time: 120, config: "config/PhysiCell_settings.xml", validation_output_folder: ""},
         ]
         platform: [
-          {"os": "windows-latest", "c_compiler": "cl", "cpp_compiler": "cl", "build_physiboss": "OFF"},
+          {"os": "windows-latest", "c_compiler": "cl", "cpp_compiler": "cl", "build_physiboss": "ON"},
           {"os": "ubuntu-latest", "c_compiler": "gcc", "cpp_compiler": "g++", "build_physiboss": "ON"},
           {"os": "ubuntu-latest", "c_compiler": "clang", "cpp_compiler": "clang++", "build_physiboss": "ON"},
           {"os": "macos-latest", "c_compiler": "gcc-15", "cpp_compiler": "g++-15", "build_physiboss": "ON"},
diff --git a/addons/PhysiBoSS/CMakeLists.txt b/addons/PhysiBoSS/CMakeLists.txt
index 8ea5b2cce..e7ab48ca1 100644
--- a/addons/PhysiBoSS/CMakeLists.txt
+++ b/addons/PhysiBoSS/CMakeLists.txt
@@ -1,4 +1,4 @@
-set(MABOSS_VERSION v2.5.6)
+set(MABOSS_VERSION v2.6.5.3)
 
 function(create_physiboss_target MAX_NODES)
   set(TARGET_NAME PhysiBoSS_${MAX_NODES}n)
@@ -25,7 +25,11 @@ function(create_physiboss_target MAX_NODES)
                                                  STREQUAL "arm64")
     set(MABOSS_ARCHIVE libMaBoSS-macos-arm64.tar.gz)
   elseif(CMAKE_SYSTEM_NAME STREQUAL "Windows")
-    set(MABOSS_ARCHIVE libMaBoSS-win64.tar.gz)
+    if (MSVC)
+      set(MABOSS_ARCHIVE libMaBoSS-win64-msvc.tar.gz)
+    else()
+      set(MABOSS_ARCHIVE libMaBoSS-win64.tar.gz)
+    endif()
   else()
     message(FATAL_ERROR "Unsupported OS: ${CMAKE_SYSTEM_NAME}")
   endif()
diff --git a/addons/PhysiBoSS/setup_libmaboss.py b/addons/PhysiBoSS/setup_libmaboss.py
index 888dd2748..8fb348c56 100644
--- a/addons/PhysiBoSS/setup_libmaboss.py
+++ b/addons/PhysiBoSS/setup_libmaboss.py
@@ -20,7 +20,7 @@
     # Assume Windows
     mb_file = ""
     url = ""
-    maboss_version = "v2.5.6"
+    maboss_version = "v2.6.5.3"
     if os_type.lower() == 'darwin':
         if "ARM64" in platform.uname().version:
             mb_file = "libMaBoSS-macos-arm64.tar.gz"
diff --git a/addons/PhysiBoSS/src/maboss_network.h b/addons/PhysiBoSS/src/maboss_network.h
index 5aace16d3..869106796 100644
--- a/addons/PhysiBoSS/src/maboss_network.h
+++ b/addons/PhysiBoSS/src/maboss_network.h
@@ -1,9 +1,7 @@
 #ifndef _MaBoSS_Net_h_
 #define _MaBoSS_Net_h_
 
-#include "StochasticSimulationEngine.h"
-#include "BooleanNetwork.h"
-#include "RunConfig.h"
+#include "engines/StochasticSimulationEngine.h"
 #include "../../../core/PhysiCell_utilities.h"
 
 /**