diff --git a/news/images/isoform_usage_post.jpg b/news/images/isoform_usage_post.jpg
index 727cddeaf8518..23249fc5d1883 100644
Binary files a/news/images/isoform_usage_post.jpg and b/news/images/isoform_usage_post.jpg differ
diff --git a/topics/ai4life/images/contribute_model.png b/topics/ai4life/images/contribute_model.png
index 058e9d7106233..d82f76136a0c1 100644
Binary files a/topics/ai4life/images/contribute_model.png and b/topics/ai4life/images/contribute_model.png differ
diff --git a/topics/ai4life/images/contribute_model_upload_1.png b/topics/ai4life/images/contribute_model_upload_1.png
index 9ef4e5c698ba3..864ad9d9cfca4 100644
Binary files a/topics/ai4life/images/contribute_model_upload_1.png and b/topics/ai4life/images/contribute_model_upload_1.png differ
diff --git a/topics/ai4life/images/contribute_model_upload_2.png b/topics/ai4life/images/contribute_model_upload_2.png
index 64348119e23a8..d147987622052 100644
Binary files a/topics/ai4life/images/contribute_model_upload_2.png and b/topics/ai4life/images/contribute_model_upload_2.png differ
diff --git a/topics/ai4life/images/contribute_model_upload_3.png b/topics/ai4life/images/contribute_model_upload_3.png
index 412ae4268ab2d..0bf089ffd014b 100644
Binary files a/topics/ai4life/images/contribute_model_upload_3.png and b/topics/ai4life/images/contribute_model_upload_3.png differ
diff --git a/topics/dev/images/ToolFactory_big_picture.png b/topics/dev/images/ToolFactory_big_picture.png
index 2d9db76c55eab..d9487581fe530 100644
Binary files a/topics/dev/images/ToolFactory_big_picture.png and b/topics/dev/images/ToolFactory_big_picture.png differ
diff --git a/topics/evolution/tutorials/mtb_phylogeny/images/tree_unrooted_galaxy_vis.png b/topics/evolution/tutorials/mtb_phylogeny/images/tree_unrooted_galaxy_vis.png
index 8267d6dc16925..e4e6ec25ba2e8 100644
Binary files a/topics/evolution/tutorials/mtb_phylogeny/images/tree_unrooted_galaxy_vis.png and b/topics/evolution/tutorials/mtb_phylogeny/images/tree_unrooted_galaxy_vis.png differ
diff --git a/topics/introduction/images/101_displayucsc.png b/topics/introduction/images/101_displayucsc.png
index 4c8406dcd5e92..f6c316bc8a715 100644
Binary files a/topics/introduction/images/101_displayucsc.png and b/topics/introduction/images/101_displayucsc.png differ
diff --git a/topics/introduction/images/101_ucsc_visualize.png b/topics/introduction/images/101_ucsc_visualize.png
index 44a1e2626bcc0..728bfbaf0714d 100644
Binary files a/topics/introduction/images/101_ucsc_visualize.png and b/topics/introduction/images/101_ucsc_visualize.png differ
diff --git a/topics/metagenomics/images/metatranscriptomics/graphlan.png b/topics/metagenomics/images/metatranscriptomics/graphlan.png
index bb28130a3cea3..325561c0831e0 100644
Binary files a/topics/metagenomics/images/metatranscriptomics/graphlan.png and b/topics/metagenomics/images/metatranscriptomics/graphlan.png differ
diff --git a/topics/metagenomics/images/metatranscriptomics/krona.png b/topics/metagenomics/images/metatranscriptomics/krona.png
index 870af944a69e1..0d09c1b7ca011 100644
Binary files a/topics/metagenomics/images/metatranscriptomics/krona.png and b/topics/metagenomics/images/metatranscriptomics/krona.png differ
diff --git a/topics/metagenomics/images/metatranscriptomics/krona_bacteria.png b/topics/metagenomics/images/metatranscriptomics/krona_bacteria.png
index e15ab04a4e4df..fa7acf2015286 100644
Binary files a/topics/metagenomics/images/metatranscriptomics/krona_bacteria.png and b/topics/metagenomics/images/metatranscriptomics/krona_bacteria.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics-short/images/graphlan.png b/topics/metagenomics/tutorials/metatranscriptomics-short/images/graphlan.png
index bb28130a3cea3..325561c0831e0 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics-short/images/graphlan.png and b/topics/metagenomics/tutorials/metatranscriptomics-short/images/graphlan.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona.png b/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona.png
index 870af944a69e1..0d09c1b7ca011 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona.png and b/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona_bacteria.png b/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona_bacteria.png
index e15ab04a4e4df..fa7acf2015286 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona_bacteria.png and b/topics/metagenomics/tutorials/metatranscriptomics-short/images/krona_bacteria.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics/images/graphlan.png b/topics/metagenomics/tutorials/metatranscriptomics/images/graphlan.png
index bb28130a3cea3..325561c0831e0 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics/images/graphlan.png and b/topics/metagenomics/tutorials/metatranscriptomics/images/graphlan.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics/images/krona.png b/topics/metagenomics/tutorials/metatranscriptomics/images/krona.png
index 870af944a69e1..0d09c1b7ca011 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics/images/krona.png and b/topics/metagenomics/tutorials/metatranscriptomics/images/krona.png differ
diff --git a/topics/metagenomics/tutorials/metatranscriptomics/images/krona_bacteria.png b/topics/metagenomics/tutorials/metatranscriptomics/images/krona_bacteria.png
index e15ab04a4e4df..fa7acf2015286 100644
Binary files a/topics/metagenomics/tutorials/metatranscriptomics/images/krona_bacteria.png and b/topics/metagenomics/tutorials/metatranscriptomics/images/krona_bacteria.png differ
diff --git a/topics/single-cell/images/scrna-pre-processing/tenx_cells.png b/topics/single-cell/images/scrna-pre-processing/tenx_cells.png
index 85ba545819679..a6f50a012cbbf 100644
Binary files a/topics/single-cell/images/scrna-pre-processing/tenx_cells.png and b/topics/single-cell/images/scrna-pre-processing/tenx_cells.png differ
diff --git a/topics/single-cell/images/scrna-pre-processing/tenx_knee.png b/topics/single-cell/images/scrna-pre-processing/tenx_knee.png
index ec5fb5ec3e539..14fe74c939bfe 100644
Binary files a/topics/single-cell/images/scrna-pre-processing/tenx_knee.png and b/topics/single-cell/images/scrna-pre-processing/tenx_knee.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/CPAT_distributions.jpg b/topics/transcriptomics/images/differential_isoform/CPAT_distributions.jpg
index 7784f849a019b..385454c473cd9 100644
Binary files a/topics/transcriptomics/images/differential_isoform/CPAT_distributions.jpg and b/topics/transcriptomics/images/differential_isoform/CPAT_distributions.jpg differ
diff --git a/topics/transcriptomics/images/differential_isoform/consequences_dataset.png b/topics/transcriptomics/images/differential_isoform/consequences_dataset.png
index eb1840a947e72..52728fc0df87a 100644
Binary files a/topics/transcriptomics/images/differential_isoform/consequences_dataset.png and b/topics/transcriptomics/images/differential_isoform/consequences_dataset.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/differential_cancer.png b/topics/transcriptomics/images/differential_isoform/differential_cancer.png
index 707a1b266fa34..de0991f6bbfb1 100644
Binary files a/topics/transcriptomics/images/differential_isoform/differential_cancer.png and b/topics/transcriptomics/images/differential_isoform/differential_cancer.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/fastqc_per_base_sequence_quality.png b/topics/transcriptomics/images/differential_isoform/fastqc_per_base_sequence_quality.png
index dbcffdfcb8a2f..5cf7113146071 100644
Binary files a/topics/transcriptomics/images/differential_isoform/fastqc_per_base_sequence_quality.png and b/topics/transcriptomics/images/differential_isoform/fastqc_per_base_sequence_quality.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_features.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_features.png
index 4adc8c8216eee..504a241b9b6c6 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_features.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_features.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform.png
index b24851c2f2720..059814820ed74 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform_fulldata.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform_fulldata.png
index 4107dcb022c73..1a4c3369ffe8e 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform_fulldata.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_consequences_isoform_fulldata.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_gene.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_gene.png
index 343527f46d156..6ed626a7c8126 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_gene.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_gene.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_isoform_usage.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_isoform_usage.png
index 0381ab0543d31..17691b82e5ee0 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_isoform_usage.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_isoform_usage.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event.png
index 60124692b1abc..c221b8f62de7d 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event_fulldata.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event_fulldata.png
index fabeaef3b6faa..613765af4ce06 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event_fulldata.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_splicing_event_fulldata.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_summary.png b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_summary.png
index 65dee72cd382e..e20333bf1f364 100644
Binary files a/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_summary.png and b/topics/transcriptomics/images/differential_isoform/isoformSwitchAnalyzer_summary.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/list_genes.png b/topics/transcriptomics/images/differential_isoform/list_genes.png
index aa88e0632dcd5..29ca092779e48 100644
Binary files a/topics/transcriptomics/images/differential_isoform/list_genes.png and b/topics/transcriptomics/images/differential_isoform/list_genes.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/pgt_RGMB_zoom_out.png b/topics/transcriptomics/images/differential_isoform/pgt_RGMB_zoom_out.png
index d6e46c614e75a..60dc451fb0d95 100644
Binary files a/topics/transcriptomics/images/differential_isoform/pgt_RGMB_zoom_out.png and b/topics/transcriptomics/images/differential_isoform/pgt_RGMB_zoom_out.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/rseqc_gene_body_coverage_plot.png b/topics/transcriptomics/images/differential_isoform/rseqc_gene_body_coverage_plot.png
index 1af74d8a82e76..82f95ad471ef3 100644
Binary files a/topics/transcriptomics/images/differential_isoform/rseqc_gene_body_coverage_plot.png and b/topics/transcriptomics/images/differential_isoform/rseqc_gene_body_coverage_plot.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/rseqc_infer_experiment_plot.png b/topics/transcriptomics/images/differential_isoform/rseqc_infer_experiment_plot.png
index 9a61ae5f2df12..fc65e7d6c4d07 100644
Binary files a/topics/transcriptomics/images/differential_isoform/rseqc_infer_experiment_plot.png and b/topics/transcriptomics/images/differential_isoform/rseqc_infer_experiment_plot.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/rseqc_junction_annotation_junctions_plot.png b/topics/transcriptomics/images/differential_isoform/rseqc_junction_annotation_junctions_plot.png
index 686008c013a8a..b545ec803068b 100644
Binary files a/topics/transcriptomics/images/differential_isoform/rseqc_junction_annotation_junctions_plot.png and b/topics/transcriptomics/images/differential_isoform/rseqc_junction_annotation_junctions_plot.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/rseqc_junction_saturation_plot.png b/topics/transcriptomics/images/differential_isoform/rseqc_junction_saturation_plot.png
index c298eff0bddff..a4cd7df4fedc4 100644
Binary files a/topics/transcriptomics/images/differential_isoform/rseqc_junction_saturation_plot.png and b/topics/transcriptomics/images/differential_isoform/rseqc_junction_saturation_plot.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/rseqc_read_distribution_plot.png b/topics/transcriptomics/images/differential_isoform/rseqc_read_distribution_plot.png
index 176c858981ef5..d1d5287072709 100644
Binary files a/topics/transcriptomics/images/differential_isoform/rseqc_read_distribution_plot.png and b/topics/transcriptomics/images/differential_isoform/rseqc_read_distribution_plot.png differ
diff --git a/topics/transcriptomics/images/differential_isoform/scheme.jpeg b/topics/transcriptomics/images/differential_isoform/scheme.jpeg
index 1bb2e8ebc2414..e36426c0328c5 100644
Binary files a/topics/transcriptomics/images/differential_isoform/scheme.jpeg and b/topics/transcriptomics/images/differential_isoform/scheme.jpeg differ
diff --git a/topics/transcriptomics/images/differential_isoform/star_alignment.png b/topics/transcriptomics/images/differential_isoform/star_alignment.png
index 3154275fd772f..8ad322ee8f68f 100644
Binary files a/topics/transcriptomics/images/differential_isoform/star_alignment.png and b/topics/transcriptomics/images/differential_isoform/star_alignment.png differ
diff --git a/topics/variant-analysis/images/pox-virus-tiled-amplicon/pox-tiled-amplicon-wf.png b/topics/variant-analysis/images/pox-virus-tiled-amplicon/pox-tiled-amplicon-wf.png
index 32a4de2b58bc0..7c2c216a7a084 100644
Binary files a/topics/variant-analysis/images/pox-virus-tiled-amplicon/pox-tiled-amplicon-wf.png and b/topics/variant-analysis/images/pox-virus-tiled-amplicon/pox-tiled-amplicon-wf.png differ
diff --git a/topics/variant-analysis/images/sars-cov-2-variant-discovery/schema.png b/topics/variant-analysis/images/sars-cov-2-variant-discovery/schema.png
index eb7a3607715a8..0edd3207bcb74 100644
Binary files a/topics/variant-analysis/images/sars-cov-2-variant-discovery/schema.png and b/topics/variant-analysis/images/sars-cov-2-variant-discovery/schema.png differ