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In this re-submission:
- Used bibentry() instead of citEntry() in the inst/CITATION file as suggested by the CRAN team.
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- In previous versions, the functionality of the
uniq_pep
parameter (seecreate_df
help page) was incorrectly described. We corrected the description to match its functionality as follows: "Numerical. Proteins that are identified by this number or fewer number of unique peptides are filtered out (default is 2).Only applies wheninput_type = "MaxQuant"
.
- In previous versions,
volcano_plot
function plotted "-log10(P-value)" on the y-axis by default even whensig = "adjP"
and only colored the dots by their significance based on "adjP". In this version,sig = "adjP"
shows "-log10.adj. P-value" on the y-axis and colors the dots by their "adjP" significance.
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- A new argument (
data_type
) added to thecreate_df
function to accommodate other types of LFQ data (raw intensity, iBAQ).
- A new argument
input_type
added to thecreate_df
function to allow users to input data from a standard quantitative matrix.
- To allow for missing data imputation prior to or after data normalization
step (depending on the imputation method used), the following changes were made:
norm_df
andimp_df
arguments replaced with a genericdf
argument in the functions,find_dep
,impute_na
,normalize_data
, andheatmap_de
- A note was added to the tutorials to clarify that for some imputation methods, such as the kNN method, data normalization should be performed prior to imputation.
naive_bayes
added to the defaultalgorithm_list
argument in thetrain_models
function.
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In this re-submission:
- Replaced "https://www.biorxiv.org/content/early/2022/08/18/2022.08.17.503867" with "https://www.biorxiv.org/content/10.1101/2022.08.17.503867v1" in the inst/CITATION file as suggested by the CRAN team.
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- Fixes a minor issue with
create_df
when removing potential contaminants. The number of potential contaminants removed is now shown in the console. - Fixes an issue with
find_dep
that previously used a fixed value for theadj_method
argument. - Fixes an issue with the
file_path
argument for saving the "TopHits.txt" file produced by thefind_dep
function.
- Citation file updated with the biorxiv preprint details.
- Readme file updated with information on the Shiny App.
- Help pages updated.
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In this re-submission:
- Added references to the DESCRIPTION file.
- Limited the use of
\dontrun
to an example that would otherwise write to the user's working directory* - Added
\donttest
to examples that are not executable in < 5 sec and unwrapped all the remaining examples* - Removed unnecessary information messages that were previously written to the console*
- Provided seed as an argument to avoid setting seed to a specific number within functions*
- Made changes in functions to write files to
tempdir()
whenfile_path
is not specified.
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