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Goldstein's Research Lab

The Group

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Dr. Goldstein

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Lab Members

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Henos Tadesse

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Skeletal Tissue Engineering and Mechanobiology Lab

Virginia Tech - Goldstein Research Lab

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About our Research

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- An estimated 2.2 million orthopedic procedures involving bone grafts are performed annually worldwide. While small breaks can heal on their own, severe injuries cannot and require surgical intervention. Current solutions, such as autologous and allogenic grafts, have inherent limitations due to supply and risks associated with disease. Goldstein's research group aims to create a bioactive, tissue engineered scaffold (TENGS) that will aid in the regeneration process and overcome current challenges. Current projects investigate poly(1,8 octane-diol) co-citric acid, polyurethanes, and poly(glycerol sebacate). We are creating 3-dimensional TENGS in addition to micro-fibrous meshes for varying orthopedic applications. Once the scaffols are fabricated, the students are able to test their mechanical, biological, and chemical properties using methods such as tensile tests, DSC, cell culturing, etc. + + An estimated 2.2 million orthopedic procedures involving bone grafts are performed annually worldwide. While small breaks can heal on their own, severe injuries cannot and require surgical intervention. Current solutions, such as autologous and allogenic grafts, have inherent limitations due to supply and risks associated with disease. Goldstein's research group aims to create a bioactive, tissue engineered scaffold (TENGS) that will aid in the regeneration process and overcome current challenges. Current projects investigate poly(1,8 octane-diol) co-citric acid, polyurethanes, and poly(glycerol sebacate). We are creating 3-dimensional TENGS in addition to micro-fibrous meshes for varying orthopedic applications. Once the scaffols are fabricated, the students are able to test their mechanical, biological, and chemical properties using methods such as tensile tests, DSC, cell culturing, etc.

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Interested in joining the team?

Contact Dr. Goldstein at goldst@vt.edu -

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