diff --git a/Cargo.lock b/Cargo.lock
index 0cf47febc3..f3b57fcae4 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -1,5 +1,7 @@
 # This file is automatically @generated by Cargo.
 # It is not intended for manual editing.
+version = 3
+
 [[package]]
 name = "ahash"
 version = "0.4.7"
@@ -159,6 +161,15 @@ dependencies = [
  "proc-macro-hack",
 ]
 
+[[package]]
+name = "indoc"
+version = "1.0.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "e7906a9fababaeacb774f72410e497a1d18de916322e33797bb2cd29baa23c9e"
+dependencies = [
+ "unindent",
+]
+
 [[package]]
 name = "indoc-impl"
 version = "0.3.6"
@@ -306,9 +317,15 @@ dependencies = [
  "ndarray",
  "num-complex",
  "num-traits",
- "pyo3",
+ "pyo3 0.12.4",
 ]
 
+[[package]]
+name = "once_cell"
+version = "1.10.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "87f3e037eac156d1775da914196f0f37741a274155e34a0b7e427c35d2a2ecb9"
+
 [[package]]
 name = "parking_lot"
 version = "0.11.1"
@@ -391,8 +408,7 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "bf6bbbe8f70d179260b3728e5d04eb012f4f0c7988e58c11433dd689cecaa72e"
 dependencies = [
  "ctor",
- "hashbrown",
- "indoc",
+ "indoc 0.3.6",
  "inventory",
  "libc",
  "parking_lot",
@@ -401,6 +417,32 @@ dependencies = [
  "unindent",
 ]
 
+[[package]]
+name = "pyo3"
+version = "0.16.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "a378727d5fdcaafd15b5afe9842cff1c25fdc43f62a162ffda2263c57ad98703"
+dependencies = [
+ "cfg-if 1.0.0",
+ "hashbrown",
+ "indoc 1.0.4",
+ "libc",
+ "parking_lot",
+ "pyo3-build-config",
+ "pyo3-ffi",
+ "pyo3-macros",
+ "unindent",
+]
+
+[[package]]
+name = "pyo3-build-config"
+version = "0.16.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "4fbb27a3e96edd34c13d97d0feefccc90a79270c577c66e19d95af8323823dfc"
+dependencies = [
+ "once_cell",
+]
+
 [[package]]
 name = "pyo3-derive-backend"
 version = "0.12.4"
@@ -412,6 +454,40 @@ dependencies = [
  "syn",
 ]
 
+[[package]]
+name = "pyo3-ffi"
+version = "0.16.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "7b719fff844bcf3f911132112ec06527eb195f6a98e0c42cf97e1118929fd4ea"
+dependencies = [
+ "libc",
+ "pyo3-build-config",
+]
+
+[[package]]
+name = "pyo3-macros"
+version = "0.16.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "f795e52d3320abb349ca28b501a7112154a87f353fae1c811deecd58e99cfa9b"
+dependencies = [
+ "proc-macro2",
+ "pyo3-macros-backend",
+ "quote",
+ "syn",
+]
+
+[[package]]
+name = "pyo3-macros-backend"
+version = "0.16.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "39e03aa57a3bb7b96982958088df38302a139df4eef54671bc595f26556cb75b"
+dependencies = [
+ "proc-macro2",
+ "pyo3-build-config",
+ "quote",
+ "syn",
+]
+
 [[package]]
 name = "pyo3cls"
 version = "0.12.4"
@@ -527,7 +603,7 @@ dependencies = [
  "ndarray",
  "numpy",
  "petgraph",
- "pyo3",
+ "pyo3 0.16.2",
  "rand",
  "rand_pcg",
  "rayon",
@@ -564,9 +640,9 @@ checksum = "f7fe0bb3479651439c9112f72b6c505038574c9fbb575ed1bf3b797fa39dd564"
 
 [[package]]
 name = "unindent"
-version = "0.1.7"
+version = "0.1.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f14ee04d9415b52b3aeab06258a3f07093182b88ba0f9b8d203f211a7a7d41c7"
+checksum = "514672a55d7380da379785a4d70ca8386c8883ff7eaae877be4d2081cebe73d8"
 
 [[package]]
 name = "wasi"
diff --git a/Cargo.toml b/Cargo.toml
index 6fa1831bc2..0541e5b03b 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -25,7 +25,7 @@ rand_pcg = "0.3"
 rayon = "1.5"
 
 [dependencies.pyo3]
-version = "0.12.3"
+version = "0.16.2"
 features = ["extension-module", "hashbrown"]
 
 [dependencies.hashbrown]