diff --git a/preprocessing/nextclade/environment.yml b/preprocessing/nextclade/environment.yml
index 00ea4e06e3..5b8b2dbcd1 100644
--- a/preprocessing/nextclade/environment.yml
+++ b/preprocessing/nextclade/environment.yml
@@ -4,19 +4,19 @@ channels:
   - bioconda
   - nodefaults
 dependencies:
-  - python=3.14.2
+  - python=3.14.3
   - biopython=1.86
   - dpath=2.2.0
   - nextclade=3.18.1
   - pip=25.2
-  - uv=0.9.29
+  - uv=0.10.7
   - PyYAML=6.0.3
   - pyjwt=2.11.0
   - python-dateutil=2.9.0.post0
   - pytz=2025.2
   - requests=2.32.5
-  - pandas=3.0.0
-  - ruff=0.15.0
+  - pandas=3.0.1
+  - ruff=0.15.4
   - types-PyYAML=6.0.12.20250915
   - types-requests=2.32.4.20260107
   - types-python-dateutil=2.9.0.20260124
@@ -24,4 +24,4 @@ dependencies:
   - unidecode=1.4.0
   - pytest=9.0.2
   - pydantic=2.12.5
-  - diamond=2.1.21
+  - diamond=2.1.23