diff --git a/scripts/griffe_check.py b/scripts/griffe_check.py
new file mode 100644
index 0000000000..475dfba837
--- /dev/null
+++ b/scripts/griffe_check.py
@@ -0,0 +1,65 @@
+import argparse
+import sys
+
+import griffe
+from eachdist import find_projectroot, find_targets
+
+
+def get_modules() -> list[str]:
+    rootpath = find_projectroot()
+    targets = find_targets("DEFAULT", rootpath)
+
+    dirs_to_exclude = [
+        "docs",
+        "scripts",
+        "opentelemetry-docker-tests",
+        "examples",
+        "_template",
+    ]
+
+    packages = []
+    for target in targets:
+        rel_path = target.relative_to(rootpath)
+        if not any(excluded in str(rel_path) for excluded in dirs_to_exclude):
+            packages.append(str(rel_path / "src"))
+    return packages
+
+
+def main():
+    parser = argparse.ArgumentParser(
+        description="Check for breaking changes using griffe",
+        formatter_class=argparse.ArgumentDefaultsHelpFormatter,
+    )
+
+    parser.add_argument(
+        "--module",
+        default="opentelemetry",
+        help="Name of the module to check for breaking changes (e.g., opentelemetry, opentelemetry.sdk, opentelemetry.sdk.resources)",
+    )
+    parser.add_argument(
+        "--against",
+        default="main",
+        help="Git ref to compare against (e.g., branch, tag, or commit)",
+    )
+    args = parser.parse_args()
+
+    modules = get_modules()
+    base = griffe.load(args.module, search_paths=modules)
+    against = griffe.load_git(
+        args.module, ref=args.against, search_paths=modules
+    )
+
+    breakages = list(griffe.find_breaking_changes(against, base))
+
+    if breakages:
+        for b in breakages:
+            # We can use `b.explain()` to get a detailed explanation of the breaking change
+            # and we can iterate over breakages to perform more complex logic
+            # like skipping per object.path or breakage type
+            print(b.explain())
+        return 1
+    return 0
+
+
+if __name__ == "__main__":
+    sys.exit(main())
diff --git a/tox.ini b/tox.ini
index 997436f7d0..369a0e9acf 100644
--- a/tox.ini
+++ b/tox.ini
@@ -311,11 +311,14 @@ commands_post =
   docker-compose down -v
 
 [testenv:public-symbols-check]
-basepython: python3
 recreate = True
 deps =
   GitPython==3.1.40
+  griffe==1.7.3
+  toml
 commands =
+  ; griffe check before to fail fast if there are any issues
+  python {toxinidir}/scripts/griffe_check.py
   python {toxinidir}/scripts/public_symbols_checker.py
 
 [testenv:generate-workflows]