diff --git a/ci-operator/config/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18.yaml b/ci-operator/config/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18.yaml
index 1f651b366508e..19231a7e630e6 100644
--- a/ci-operator/config/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18.yaml
+++ b/ci-operator/config/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18.yaml
@@ -55,6 +55,32 @@ tests:
     - chain: openshift-upgrade-qe-sanity
     workflow: openshift-qe-installer-vsphere-ipi-ovn
   timeout: 8h0m0s
+- always_run: false
+  as: loaded-upgrade-418to419-12nodes-udn
+  steps:
+    allow_skip_on_success: true
+    cluster_profile: vsphere-connected-2
+    env:
+      CHURN: "false"
+      GC: "false"
+      ITERATION_MULTIPLIER_ENV: "9"
+      MAX_UNAVAILABLE_WORKER: "3"
+      OPENSHIFT_INFRA_NODE_CPU_CORE_PER_SOCKET_COUNT: "2"
+      OPENSHIFT_INFRA_NODE_CPU_COUNT: "16"
+      OPENSHIFT_INFRA_NODE_MEMORY_SIZE: "65536"
+      OPENSHIFT_INFRA_NODE_VOLUME_SIZE: "120"
+      SET_ENV_BY_PLATFORM: custom
+      VERSION: "4.18"
+      WORKER_REPLICA_COUNT: "12"
+    post:
+    - ref: openshift-qe-kube-burner-index
+    test:
+    - chain: openshift-qe-upgrade-max-unavailable
+    - ref: workers-scale
+    - chain: openshift-qe-udn-density-pods
+    - chain: openshift-upgrade-qe-sanity
+    workflow: openshift-qe-installer-vsphere-ipi-ovn
+  timeout: 8h0m0s
 zz_generated_metadata:
   branch: main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18
   org: openshift-eng
diff --git a/ci-operator/jobs/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18-presubmits.yaml b/ci-operator/jobs/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18-presubmits.yaml
index 7504be900bd3b..3d5eb602f1c58 100644
--- a/ci-operator/jobs/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18-presubmits.yaml
+++ b/ci-operator/jobs/openshift-eng/ocp-qe-perfscale-ci/openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18-presubmits.yaml
@@ -1,5 +1,80 @@
 presubmits:
   openshift-eng/ocp-qe-perfscale-ci:
+  - agent: kubernetes
+    always_run: false
+    branches:
+    - ^main_vsphere-4\.19-nightly-x86-loaded-upgrade-from-4\.18$
+    - ^main_vsphere-4\.19-nightly-x86-loaded-upgrade-from-4\.18-
+    cluster: vsphere02
+    context: ci/prow/loaded-upgrade-418to419-12nodes-udn
+    decorate: true
+    decoration_config:
+      skip_cloning: true
+      timeout: 8h0m0s
+    labels:
+      ci-operator.openshift.io/cloud: vsphere
+      ci-operator.openshift.io/cloud-cluster-profile: vsphere-connected-2
+      ci.openshift.io/generator: prowgen
+      pj-rehearse.openshift.io/can-be-rehearsed: "true"
+    name: pull-ci-openshift-eng-ocp-qe-perfscale-ci-main_vsphere-4.19-nightly-x86-loaded-upgrade-from-4.18-loaded-upgrade-418to419-12nodes-udn
+    rerun_command: /test loaded-upgrade-418to419-12nodes-udn
+    spec:
+      containers:
+      - args:
+        - --gcs-upload-secret=/secrets/gcs/service-account.json
+        - --image-import-pull-secret=/etc/pull-secret/.dockerconfigjson
+        - --lease-server-credentials-file=/etc/boskos/credentials
+        - --report-credentials-file=/etc/report/credentials
+        - --secret-dir=/secrets/ci-pull-credentials
+        - --target=loaded-upgrade-418to419-12nodes-udn
+        command:
+        - ci-operator
+        image: ci-operator:latest
+        imagePullPolicy: Always
+        name: ""
+        resources:
+          requests:
+            cpu: 10m
+        volumeMounts:
+        - mountPath: /etc/boskos
+          name: boskos
+          readOnly: true
+        - mountPath: /secrets/ci-pull-credentials
+          name: ci-pull-credentials
+          readOnly: true
+        - mountPath: /secrets/gcs
+          name: gcs-credentials
+          readOnly: true
+        - mountPath: /secrets/manifest-tool
+          name: manifest-tool-local-pusher
+          readOnly: true
+        - mountPath: /etc/pull-secret
+          name: pull-secret
+          readOnly: true
+        - mountPath: /etc/report
+          name: result-aggregator
+          readOnly: true
+      serviceAccountName: ci-operator
+      volumes:
+      - name: boskos
+        secret:
+          items:
+          - key: credentials
+            path: credentials
+          secretName: boskos-credentials
+      - name: ci-pull-credentials
+        secret:
+          secretName: ci-pull-credentials
+      - name: manifest-tool-local-pusher
+        secret:
+          secretName: manifest-tool-local-pusher
+      - name: pull-secret
+        secret:
+          secretName: registry-pull-credentials
+      - name: result-aggregator
+        secret:
+          secretName: result-aggregator
+    trigger: (?m)^/test( | .* )(loaded-upgrade-418to419-12nodes-udn|remaining-required),?($|\s.*)
   - agent: kubernetes
     always_run: false
     branches: