diff --git a/README.md b/README.md
index 5c1941d18..6c809c783 100644
--- a/README.md
+++ b/README.md
@@ -69,6 +69,7 @@ Some examples require extra dependencies. See each sample's directory for specif
 * [message_passing/introduction](message_passing/introduction/) - Introduction to queries, signals, and updates.
 * [message_passing/safe_message_handlers](message_passing/safe_message_handlers/) - Safely handling updates and signals.
 * [message_passing/update_with_start/lazy_initialization](message_passing/update_with_start/lazy_initialization/) - Use update-with-start to update a Shopping Cart, starting it if it does not exist.
+* [mutex](mutex) - lock a particular resource within a namespace between workflows.
 * [open_telemetry](open_telemetry) - Trace workflows with OpenTelemetry.
 * [patching](patching) - Alter workflows safely with `patch` and `deprecate_patch`.
 * [polling](polling) - Recommended implementation of an activity that needs to periodically poll an external resource waiting its successful completion.
diff --git a/mutex/README.md b/mutex/README.md
new file mode 100644
index 000000000..6fa657641
--- /dev/null
+++ b/mutex/README.md
@@ -0,0 +1,31 @@
+# Mutex
+
+This mutex workflow demos an ability to lock/unlock a particular resource within a particular Temporal namespace
+so that other workflows within the same namespace would wait until a resource lock is released. This is useful 
+when we want to avoid race conditions or parallel mutually exclusive operations on the same resource.
+
+One way of coordinating parallel processing is to use Temporal signals with [`start_signal`](https://docs.temporal.io/develop/python/message-passing#signal-with-start) and
+make sure signals are getting processed sequentially, however the logic might become too complex if we
+need to lock two or more resources at the same time. Mutex workflow pattern can simplify that.
+
+This example enqueues two long running `SampleWorkflowWithMutex` workflows in parallel. And each of the workflows has a mutex section (lasting 2 seconds in this example). 
+When `SampleWorkflowWithMutex` reaches the mutex section, it starts a mutex workflow via local activity, and blocks until
+`acquire-lock-event` is received. Once `acquire-lock-event` is received, it enters critical section,
+and finally releases the lock once processing is over by sending `release_lock` a signal to the `MutexWorkflow`.
+
+## Run this sample
+
+
+To run, first see [README.md](../README.md) for prerequisites. Then, run the following from this directory to start the
+worker:
+
+    uv run worker.py
+
+This will start the worker. Then, in another terminal, run the following to execute the workflows:
+
+    uv run starter.py
+
+This will start a worker to run your workflow and activities, then start two SampleWorkflowWithMutex in parallel, both locking on the same ressource.
+
+The starter terminal should complete with the workflows IDs and the worker terminal should show the logs with the locking.
+
diff --git a/mutex/mutexworkflow.py b/mutex/mutexworkflow.py
new file mode 100644
index 000000000..542cd7e57
--- /dev/null
+++ b/mutex/mutexworkflow.py
@@ -0,0 +1,117 @@
+from dataclasses import dataclass
+from temporalio.client import Client
+from temporalio import activity, workflow
+import asyncio
+from temporalio.exceptions import ApplicationError
+
+LOCK_ACQUIRED_SIGNAL_NAME = "acquire-lock-event"
+
+
+@dataclass
+class SignalWithStartMutexWorkflowInput:
+    namespace: str
+    resource_id: str
+    unlock_timeout_seconds: float
+    sender_workflow_id: str
+
+
+@dataclass
+class SignalWithStartMutexWorkflowResult:
+    workflow_id: str
+
+
+@dataclass
+class MutexWorkflowInput:
+    namespace: str
+    resource_id: str
+    unlock_timeout_seconds: float
+
+
+@activity.defn
+async def signal_with_start_mutex_workflow(
+    params: SignalWithStartMutexWorkflowInput,
+) -> SignalWithStartMutexWorkflowResult:
+    # Create client connected to server at the given address
+    client = await Client.connect("localhost:7233")
+
+    workflow_id = f"mutex:{params.namespace}:{params.resource_id}"
+
+    # Sends a signal to the workflow (and starts it if needed)
+    wf_input = MutexWorkflowInput(
+        namespace=params.namespace,
+        resource_id=params.resource_id,
+        unlock_timeout_seconds=params.unlock_timeout_seconds,
+    )
+    await client.start_workflow(
+        workflow=MutexWorkflow.run,
+        arg=wf_input,
+        id=workflow_id,
+        task_queue="mutex-task-queue",
+        start_signal="request_lock",
+        start_signal_args=[params.sender_workflow_id],
+    )
+    return SignalWithStartMutexWorkflowResult(workflow_id=workflow_id)
+
+
+def generate_unlock_token(sender_workflow_id: str) -> str:
+    return f"unlock-event-{sender_workflow_id}"
+
+
+@workflow.defn
+class MutexWorkflow:
+    def __init__(self):
+        self._lock_requests: asyncio.Queue[str] = asyncio.Queue()
+        self._lock_releases: asyncio.Queue[str] = asyncio.Queue()
+
+    @workflow.run
+    async def run(self, params: MutexWorkflowInput) -> str:
+        workflow.logger.info(f"Starting mutex workflow {workflow.info().workflow_id}")
+        while True:
+            # read lock signal
+            if self._lock_requests.empty():
+                break
+            sender_workflow_id = self._lock_requests.get_nowait()
+
+            # send release info to origin
+            # TODO manage case when origin is closed
+            unlock_token = generate_unlock_token(sender_workflow_id)
+            handle = workflow.get_external_workflow_handle(sender_workflow_id)
+            try:
+                await handle.signal(LOCK_ACQUIRED_SIGNAL_NAME, unlock_token)
+            except ApplicationError as e:
+                if e.type == "ExternalWorkflowExecutionNotFound":
+                    workflow.logger.warning(
+                        f"Could not signal lock acquisition to caller {sender_workflow_id}: {e.message}"
+                    )
+                    continue
+                else:
+                    raise e
+
+            # wait for release signal or timeout
+            try:
+                await workflow.wait_condition(
+                    lambda: not self._lock_releases.empty(),
+                    timeout=params.unlock_timeout_seconds,
+                )
+                # pop the release
+                # TODO check it’s the right one
+                if not self._lock_releases.empty():
+                    self._lock_releases.get_nowait()
+
+            # If timeout was reached, we release the lock
+            except asyncio.TimeoutError:
+                workflow.logger.warning(
+                    f"Workflow {sender_workflow_id} did not release the lock before timeout was reached."
+                )
+                continue
+        workflow.logger.info(f"Stopping mutex workflow {workflow.info().workflow_id}")
+
+    @workflow.signal
+    async def request_lock(self, sender_workflow_id: str):
+        workflow.logger.info(f"Received lock request from {sender_workflow_id}")
+        await self._lock_requests.put(sender_workflow_id)
+
+    @workflow.signal
+    async def release_lock(self, unlock_token: str):
+        workflow.logger.info(f"Received lock release with token {unlock_token}")
+        await self._lock_releases.put(unlock_token)
diff --git a/mutex/starter.py b/mutex/starter.py
new file mode 100644
index 000000000..57d34f7ea
--- /dev/null
+++ b/mutex/starter.py
@@ -0,0 +1,37 @@
+from temporalio.client import Client
+import logging
+from uuid import uuid4
+from workflow import SampleWorkflowWithMutex
+import asyncio
+
+
+async def main():
+    # set up logging facility
+    logging.basicConfig(
+        level=logging.INFO, format="%(asctime)s %(levelname)s %(message)s"
+    )
+    # Start client
+    client = await Client.connect("localhost:7233")
+
+    resource_id = uuid4()
+
+    print("starting first workflow")
+    workflow_1 = client.execute_workflow(
+        SampleWorkflowWithMutex.run,
+        str(resource_id),
+        id="sample-workflow-with-mutex-1-workflow-id",
+        task_queue="mutex-task-queue",
+    )
+    print("starting second workflow")
+    workflow_2 = client.execute_workflow(
+        SampleWorkflowWithMutex.run,
+        str(resource_id),
+        id="sample-workflow-with-mutex-2-workflow-id",
+        task_queue="mutex-task-queue",
+    )
+    results = await asyncio.gather(workflow_1, workflow_2)
+    print("results:", *results)
+
+
+if __name__ == "__main__":
+    asyncio.run(main())
diff --git a/mutex/worker.py b/mutex/worker.py
new file mode 100644
index 000000000..e4312c536
--- /dev/null
+++ b/mutex/worker.py
@@ -0,0 +1,37 @@
+import asyncio
+import logging
+
+from temporalio.client import Client
+from temporalio.worker import Worker
+from mutexworkflow import MutexWorkflow, signal_with_start_mutex_workflow
+from workflow import SampleWorkflowWithMutex
+
+# reference: https://github.com/temporalio/samples-go/blob/main/mutex/mutex_workflow.go
+
+
+interrupt_event = asyncio.Event()
+
+
+async def main():
+    # set up logging facility
+    logging.basicConfig(
+        level=logging.INFO, format="%(asctime)s %(levelname)s %(message)s"
+    )
+    # Start client
+    client = await Client.connect("localhost:7233")
+
+    # Run a worker for the workflow
+    async with Worker(
+        client,
+        task_queue="mutex-task-queue",
+        workflows=[MutexWorkflow, SampleWorkflowWithMutex],
+        activities=[signal_with_start_mutex_workflow],
+    ):
+        # Wait until interrupted
+        print("Worker started")
+        await interrupt_event.wait()
+        print("Shutting down")
+
+
+if __name__ == "__main__":
+    asyncio.run(main())
diff --git a/mutex/workflow.py b/mutex/workflow.py
new file mode 100644
index 000000000..90086584d
--- /dev/null
+++ b/mutex/workflow.py
@@ -0,0 +1,62 @@
+from typing import Callable
+from datetime import timedelta
+from temporalio import workflow
+
+from mutexworkflow import (
+    SignalWithStartMutexWorkflowInput,
+    MutexWorkflow,
+    signal_with_start_mutex_workflow,
+    LOCK_ACQUIRED_SIGNAL_NAME,
+)
+
+
+@workflow.defn
+class SampleWorkflowWithMutex:
+    def __init__(self):
+        self.unlock_token: str | None = None
+
+    @workflow.run
+    async def run(self, resource_id: str) -> str:
+        workflow.logger.info(f"Starting workflow")
+        # acquire lock
+        unlock_func = await self.lock(resource_id, timedelta(minutes=2.0))
+        # do critical work (mutex section)
+        workflow.logger.info("Doing critical work.")
+        await workflow.sleep(2.0)
+        # release lock
+        await unlock_func()
+        workflow.logger.info(f"Stopping workflow")
+        return workflow.info().workflow_id
+
+    async def lock(
+        self, resource_id: str, unlock_timeout: timedelta
+    ) -> Callable[[], None]:
+        """lock resource"""
+        # request a lock
+        params = SignalWithStartMutexWorkflowInput(
+            namespace=workflow.info().namespace,
+            sender_workflow_id=workflow.info().workflow_id,
+            resource_id=resource_id,
+            unlock_timeout_seconds=unlock_timeout.total_seconds(),
+        )
+        result = await workflow.execute_local_activity(
+            signal_with_start_mutex_workflow,
+            params,
+            start_to_close_timeout=timedelta(seconds=5.0),
+        )
+        # wait to acquire lock from mutex workflow
+        await workflow.wait_condition(lambda: self.unlock_token is not None)
+        unlock_token = self.unlock_token
+
+        # return function to unlock
+        async def unlock_function():
+            wf_handle = workflow.get_external_workflow_handle(
+                workflow_id=result.workflow_id
+            )
+            await wf_handle.signal(MutexWorkflow.release_lock, unlock_token)
+
+        return unlock_function
+
+    @workflow.signal(name=LOCK_ACQUIRED_SIGNAL_NAME)
+    def acquired_lock(self, unlock_token: str):
+        self.unlock_token = unlock_token