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docs/paper/main.pdf

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docs/paper/main.tex

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\title[StainedGlass]{StainedGlass: Making colorful dot-plots of genomic sequence}
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\author[Vollger \textit{et~al}.]{
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Mitchell R. Vollger\,$^{\text{\sfb 1,}*}$,
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Mitchell R. Vollger\,$^{\text{\sfb 1,}}$,
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Peter Kerpedjiev\,$^{\text{\sfb 2}}$,
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Adam M. Phillippy\,$^{\text{\sfb 3,*}}$,
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Adam M. Phillippy\,$^{\text{\sfb 3,}}$,
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and Evan E. Eichler\,$^{\text{\sfb 1,4,}*}$}
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\address{
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$^{\text{\sf 1}}$Genome Sciences,
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\abstract{
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\textbf{Summary:}
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Visualization of genomic repeats is often accomplished through the use of
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dot plots; however, the emergence of telomere-to-telomere assemblies
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with multi-megabase repeats requires new visualization strategies. Here,
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we introduce StainedGlass which can generate publication quality figures
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that communicate the identity and orientation of
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multi-megabase repeats while scaling to entire genomes. \\
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Visualization and analysis of genomic repeats is typically accomplished through the use of dot plots; however, the emergence of telomere-to-telomere assemblies with multi-megabase repeats requires new visualization strategies. Here, we introduce StainedGlass which can generate publication quality figures and interactive visualizations that depict the identity and orientation of multi-megabase repeat structures at a genome-wide scale. The tool can rapidly reveal higher-order structures and improve the inference of evolutionary history for some of the most complex regions of genomes.
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\\
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\textbf{Availability and implementation:}
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StainedGlass is implemented using \href{https://snakemake.github.io}{snakemake}
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and is available open source under the MIT license at
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\href{https://mrvollger.github.io/StainedGlass}{mrvollger.github.io/StainedGlass/}.\\
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StainedGlass is implemented using \href{https://snakemake.github.io}{Snakemake} and is available open source under the MIT license at \href{https://mrvollger.github.io/StainedGlass}{mrvollger.github.io/StainedGlass/}.\\
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\textbf{Contact:} \href{[email protected]}{[email protected]}\\
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}
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%%--------------------------------------------------------------------------%%
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\begin{figure*}[!tpb]%figure1
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\centerline{
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\includegraphics[width=0.95\textwidth,keepaspectratio]{figure1.png}
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\includegraphics[width=0.95\textwidth,keepaspectratio,,natwidth=7200,natheight=4800]{figure1.png}
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}
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\caption{Output from StainedGlass showing the sequence identity within human
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chromosome 8.}

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