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LucasSilvaFerreira and others added 30 commits September 16, 2022 14:55
Fixes formatting in the 'Tasks and Potential Roadmap' section
-add new scatter plot on the kl divergence data
- The new metrics is working now (The sampled final sequences were mixed with noised versions previously  )
Resolve contributor list in an independant file
LucasSilvaFerreira and others added 30 commits October 17, 2022 14:16
Linked the gdoc sheet to keep this list updated based on what we discussed at the last meeting.
Minor formatting
Add discord link for people interested in joining
Sahu, B., Hartonen, T., Pihlajamaa, P. et al. Sequence determinants of human gene regulatory elements. Nat Genet 54, 283–294 (2022). https://doi.org/10.1038/s41588-021-01009-4
https://huggingface.co/blog/annotated-diffusion)

- MILESTONE -> Conditioning is tested and working (check diagonal plot after training to see the results)  (Thanks Zach )
- Training using 1000 sequences is enought to see the results after ~1000 epochs (kl divergence going down to train and test sequences and increascing to shuffled sequences)
- Added EMA to smooth the training.
- Added a function to deal with dataload, motifs generation  and training creation
- New metrics added KL divergence tested agains (test, train, train shuffled) sequences and per component heatmap plot.
- Added a simple loss visualization using livelossplot.
- Refactored several functions to plot motif metrix ( others are inside the dataloader new class)

Contributions
Lucas Ferreira da Silva
Luca Pinello
Zach Nussbaum
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9 participants