bootLong implements the block bootstrap method inference for longitudinal microbiome data. In addition, bootLong provides tools to explore the sampling schedule and within-subject dependency.
bootLong strats with a phyloseq object and returns the confidence intervals and adjusted p-values for the differential abundance analysis.
The input phyloseq must have the count data.
Install the development version from GitHub with:
# install.packages("devtools")
devtools::install_github("PratheepaJ/bootLong")
See vignettes for the detailed workflow.