HW4_Trofimov

HW4_Trofimov/README.md

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+<img width="641" alt="Screenshot 2023-09-27 at 17 01 47" src="https://github.com/michtrofimov/HW4_Functions2/assets/92677906/d5c63a17-7f6d-43c7-b88e-a2e994877abb">
+
+# Das biotools.aminoacids
+> **The great and terrifying successor of biopython**
+
+Das biotools strikes again! Now it works only with aminoacid sequences! 
+
+## Features
+
+- **get_pI()**: Gives isoelectric point value for each aminoacid individually.
+
+- **build_scoring_matri()**: Auxiliary function for needleman_wunsch. Build a scoring matrix for amino acid pairs, which can be used in sequence alignment algorithms.
+
+- **needleman_wunsch()**: Implement the Needleman-Wunsch algorithm for global sequence alignment of two amino acid sequences.
+
+- **convert_to_3L_code()**: Converts one letter animoacid sequence to three letter aminoacid sequence.
+
+- **protein_mass()**: Calculates molecular weight of the aminoacid sequence using monoisotopic masses.
+
+- **translate_protein_rna()**: Converts aminoacid sequence to RNA sequence. For those aminoacids that are coded with more than one codon, this function randomly chooses one codon from the set.
+
+- **calculate_aa_freq()**: Calculate the frequences of aminoacids in protein sequences.
+
+## Examples
+
+- **get_pI**
+
+```python 
+calculate_pI('RAHP') -> "Sequence: RAHP. Isoelectric point of each aminoacid: [('R', 10.8), ('A', 6.0), ('H', 7.6), ('P', 6.3)]"
+```
+
+- **needleman_wunsch**
+
+```python 
+needleman_wunsch('raHP','RAQQHP') -> 'ra--HP, RAQQHP, final score: 2'
+```
+
+- **convert_to_3L_code**
+
+```python 
+convert_to_3L_code('ACDEF') -> 'Ala-Cys-Asp-Glu-Phe'
+```
+
+- **protein_mass**
+
+```python 
+protein_mass('ACDEF') -> 565.184
+```
+
+- **translate_protein_rna**
+
+```python 
+translate_protein_rna('ACDEF') -> 'GCCUGCGACGAGUUC'
+```
+
+- **calculate_aa_freq**
+
+```python
+calculate_aa_freq('ACDEF') -> {'A': 1, 'C': 1, 'D': 1, 'E': 1, 'F': 1}
+```
+
+## OUR TEAM
+<img width="800" alt="Screenshot 2023-09-30 at 16 34 25" src="https://github.com/michtrofimov/HW4_Functions2/assets/92677906/38fcc288-2d27-445d-b1dc-a3b055099a26">
+
+Up to bottom, left to right:
+- Alisa Fedorenko: functions **main**, **calculate_aa_freq**
+- Michil Trofimov: functions **get_pI**, **needleman_wunsch** (teamlead)
+- Shakir Suleimanov: functions **convert_to_3L_code**, **protein_mass**, **translate_protein_rna**
+