V-finder

A tool that automatically finds overlapping clinvar variants with Transcription Factor Binding Sights from the ReMAP2022 database.

Usage:

You first need a ReMAP2022 database file, and the clinvar txt file with all available variants.

In the example given, we took the bed file for TP53 Transcription Factor.

Code:

python code/single_cell_meta_pipeline.py bedfile.bed clinvar.txt --reference GRCh38 --out_folder results --clean