Disease dMRI Collections

Curated disease-focused MRI datasets (structural & diffusion) for research, benchmarking, and education. Each release retains its original license, citation, and metadata. Please cite the source when using any dataset.

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Included Releases

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1) Alzheimer’s vs Bipolar vs Healthy Controls (ubc-ad_bd)

Structural & diffusion MRI with derived FA, TBSS, VBM and clinical CSVs.

Download (Linux/macOS)

curl -s https://api.github.com/repos/data-hcp/disease/releases/tags/ubc-ad_bd | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

Download (Windows PowerShell)

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/disease/releases/tags/ubc-ad_bd").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

• Scope: AD, BD, and healthy controls (anonymized)
• Analyses: FSL (DTI/TBSS), SPM (VBM); registration to MNI
• License: CC BY 4.0
• Citation/DOI: Besga, Graña, Chyzhyk (2020). Zenodo. https://doi.org/10.5281/zenodo.3935636
• Use cases: AD vs BD discrimination, biomarker correlation, CAD modeling

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2) High-Quality DWI of Parkinson’s Disease (liege-pd)

Cross-sectional PD dataset with 120 dirs, b=1000/2500, 2.4 mm³ voxels; matched controls.

Download (Linux/macOS)

curl -s https://api.github.com/repos/data-hcp/disease/releases/tags/liege-pd | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

Download (Windows PowerShell)

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/disease/releases/tags/liege-pd").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

• N: 27 PD, 26 controls
• Sequence: Twice-refocused spin-echo
• License: CC BY-SA
• Source: NITRC “parktdi” (linked in release)
• Use cases: PD microstructure, group comparisons, denoising/EDDY benchmarks

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3) Inter-Site Reproducibility in Small Vessel Disease (isd-svd)

CADASIL patients scanned on Prisma & Skyra within 24 hours, BIDS-structured.

Download (Linux/macOS)

curl -s https://api.github.com/repos/data-hcp/disease/releases/tags/isd-svd | jq -r '.assets[].browser_download_url' | xargs -n1 -P4 curl -LO

Download (Windows PowerShell)

(Invoke-RestMethod "https://api.github.com/repos/data-hcp/disease/releases/tags/isd-svd").assets | ForEach-Object { Invoke-WebRequest $_.browser_download_url -OutFile (Split-Path $_.browser_download_url -Leaf) }

• N: 10 CADASIL patients
• Preproc: dwidenoise, mrdegibbs, TOPUP, EDDY
• License: CC BY-NC 4.0
• Citation/DOI: https://doi.org/10.5281/zenodo.16925507
• Paper: Neurology (2020)
• Use cases: Harmonization (ComBat/LongCombat), artifact studies, SVD biomarkers

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Licensing & Citation

• ubc-ad_bd: CC BY 4.0 — cite Besga et al., Zenodo (2020)
• liege-pd: CC BY-SA — cite NITRC source
• isd-svd: CC BY-NC 4.0 — cite Dewenter et al., Zenodo (2020) & Neurology (2020)

You must follow dataset licenses and cite the original investigators.

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Notes

• Some releases include preprocessed and raw data
• CC BY-NC datasets may impose non-commercial restrictions
• Defacing/anonymization methods differ—check for your application