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Describe your changes

Add metrics/cilisi new metric component.

CiLISI measures batch mixing in a cell type-aware manner by computing iLISI within each cell type and normalizing the scores between 0 and 1. Unlike iLISI, ciLISI preserves sensitivity to biological variance and avoids favoring overcorrected datasets with removed cell type signals.
We propose adding this metric to substitute iLISI.

More information at:

Checklist before requesting a review

  • I have performed a self-review of my code

  • Check the correct box. Does this PR contain:

    • Breaking changes
    • New functionality
    • Major changes
    • Minor changes
    • Bug fixes
  • Proposed changes are described in the CHANGELOG.md

  • CI Tests succeed and look good!

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@mumichae mumichae left a comment

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Looking great! Just some minor comments on documentation and removing boilerplate code.

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Thanks!! Requested changes addressed and resolved.

@rcannood rcannood requested a review from mumichae August 8, 2025 14:26
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rcannood commented Aug 8, 2025

@mumichae Do you have any additional feedback or can this be merged?

@JGarnica22
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Hi,

Check test failed despite running successfully locally. The issue is the same as commented in #58 (comment) . However, in this case I didn't have to turn off dependencies by the github installing.

Could be the problem given by the container when installing R dependencies?

thanks,

JGarnica22 and others added 3 commits September 17, 2025 16:00
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Hi, thanks for your help. The changes have been applied and merged to upstream/main

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@mumichae mumichae left a comment

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Looking great! Will merge

@mumichae mumichae merged commit 5331b9e into openproblems-bio:main Sep 25, 2025
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4 participants