Release v2.1.7

[ManuelTgn]

Pull Request: CRISPRme Version 2.1.7 Update

Description

This PR introduces version 2.1.7 of CRISPRme, which includes the following updates and improvements:

Key Features and Changes

🚀 New Features

• Support for Exome GNOMAD VCFs
  • Added support for exome-based gnomAD variant call format (VCF) files, expanding dataset compatibility.

🐛 Bug Fixes

• Fix 1: Corrected handling of indels in off-target reporting
  • Resolved an issue where off-targets containing indel variants were either unreported or misreported.
• Fix 2: Fixed the visualization of the Personal Card tab
  • Addressed inconsistencies in the display of personal card off-targets in the GUI and website.
• Fix 3: Closed stream after creating graphical reports
  • Ensured proper resource management by closing open streams post-report generation.

🛠 Enhancements

• Improved contiguous target merge logic
  • Enhanced merging logic to always report the leftmost off-target in target clusters, improving reproducibility across runs.
• Improved error tracing logic
  • Refined error handling to provide more informative traces, enhancing debugging capabilities.
• Upgraded Version available on DockerHub

Upgrade Instructions

To upgrade to version 2.1.7, follow these steps:

mamba create -n crisprme
mamba activate crisprme
mamba install crisprme=2.1.7

Checklist

• Code reviewed and approved.
• Tests written and passing.
• Documentation updated.

Linked Issues

Closes #73, #74 related to this release.