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PMID:36202103 #4694

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PCarme opened this issue Apr 4, 2025 · 4 comments
Closed
1 of 2 tasks

PMID:36202103 #4694

PCarme opened this issue Apr 4, 2025 · 4 comments

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@PCarme
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PCarme commented Apr 4, 2025

  • New term: decreased vesicle number at the fusion focus of mating cells
    A physical cellular phenotype in which the number of vesicles observed in a mating cell is lower than normal.

  • New term: normal cell fusion during mating
    A cellular process phenotype in which plasma membrane fusion involved in cytogamy is normal (i.e. indistinguishable from wild-type).

@ValWood
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ValWood commented Apr 7, 2025

are these exocytotic vesicles?

@ValWood
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ValWood commented Apr 7, 2025

New term: normal cell fusion during mating
A cellular process phenotype in which plasma membrane fusion involved in cytogamy is normal (i.e. indistinguishable from wild-type).

I was going to put this under 'normal mating' but I can't do that because mating might not be normal.
I think in these cases Midori added a has_part relation to "normal mating". I will try to find out but for now it will be under normal mating

@ValWood
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ValWood commented Apr 7, 2025

All secretory vesicles that release their contents outside the cell via exocytosis are exocytic vesicles, but not all exocytic vesicles are necessarily secretory in the classical sense (some might release waste or other cellular products).

we have
"exocytic vesicles present in increased numbers" (FYPO:0002086)
I will create
exocytic vesicles present in decreased numbers at the fusion focus of mating cells

and group under a parent
"abnormal exocytic vesicle number"

if it's incorrect, I can move it up and make a "secretory" parent (although we don't use secretory in GO for complicated reasons...we probably should.

ValWood added a commit that referenced this issue Apr 7, 2025
ValWood added a commit that referenced this issue Apr 7, 2025
@ValWood ValWood closed this as completed in bfa9c06 Apr 7, 2025
@PCarme
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PCarme commented Apr 8, 2025

All secretory vesicles that release their contents outside the cell via exocytosis are exocytic vesicles, but not all exocytic vesicles are necessarily secretory in the classical sense (some might release waste or other cellular products).

we have "exocytic vesicles present in increased numbers" (FYPO:0002086) I will create exocytic vesicles present in decreased numbers at the fusion focus of mating cells

and group under a parent "abnormal exocytic vesicle number"

if it's incorrect, I can move it up and make a "secretory" parent (although we don't use secretory in GO for complicated reasons...we probably should.

I think it is correct here, they describe them as "secretory vesicles carrying cell wall digestive enzymes" in the paper.

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